Bicillin L-A (Benzathine Penicillin G) Shortage

On April 29th, 2016, a Bicillin L-A (Benzathine Penicillin G) drug shortage was announced by the Food and Drug Administration (FDA). Benzathine penicillin G is the recommended treatment for syphilis and the only recommended treatment for pregnant women infected with or exposed to syphilis. Other formulations of penicillin, including Bicillin C-R, are not acceptable alternatives to Bicillin L-A for syphilis treatment. The manufacturer estimates the Bicillin L-A shortage will last until at least July, 2016. This advisory provides recommended actions and resources to help clinicians safely address the current Bicillin L-A drug shortage.

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